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MYP_025964
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Basic Information
WR8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C59H108N34O10
Standard
Sequence
WRRRRRRRR
Physicochemical Analysis
1453.71 Da
12.00
7.76
7.56
0.8622
-4.10
0.25
-2.16
454.40
0.00
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
807.11
-8.89
35.0
18.0
51.0
103.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040236 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
RECORD: Rec_0054201 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
44 μM
MIC
PMID22989747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22989747/
RECORD: Rec_0056557 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human cervical carcinoma HeLa[50% Cell death = 442+-66.7 microM]
PMID22989747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22989747/
RECORD: Rec_0099156 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
128 μM
HD50
PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
RECORD: Rec_0260868 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
WR8
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugation with FAM
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22712882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22712882/
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