Peptide Database

Peptide NameRNS7_NICAL

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length218 amino acids

Chemical FormulaC1133H1747N297O321S16

DescriptionStandard

        CPHPKTCKPTGSNEIKFPGRGMKYTVQKINSTIKKITQGYPNLSCTKGIMELVEIGICFDSMVKNVINMLNSPLTSVLFVLLFVLSPIYGAFEYMQLVLQWPTAFCHTTPCKRIPNNFQHQNFWRHEYNKHGKCCSESYNREQYFDLAMALKDKFDLLSSLRNHGIIPTIHGLWPDNVSTTLNYCAAKENFKNIEDDTKKDDLYKRWPDLTTAETYCK
    

Molecular Weight25177.83 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)6.28

Net Charge (pH 7.4) 5.51

Charge Density (pH 7.0) 0.0288

GRAVY Index-0.40

Hydrophobic Moment 0.71

Boman Index-0.00

Instability Index33.58

Aliphatic Index 74.22

Aromaticity 0.1147

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37525.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000876 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana alata [Plant]

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme