Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length164 amino acids

Chemical FormulaC815H1322N236O240S8

DescriptionStandard

        MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSVAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTCDAYKNL
    

Molecular Weight18523.17 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)7.57

Net Charge (pH 7.4) 7.21

Charge Density (pH 7.0) 0.0462

GRAVY Index-0.35

Hydrophobic Moment 0.71

Boman Index-0.08

Instability Index39.25

Aliphatic Index 88.66

Aromaticity 0.0793

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7809.60

LogP -77.96

H-bond Donors 277.0

H-bond Acceptors 257.0

Rotatable Bonds 634.0

Heavy Atoms 1299.0

Ring Count 19.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055369 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage T2 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0218607 VERIFIED: NO