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MYP_025916
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Basic Information
L-K6 [L11W]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C80H144N20O15
Standard
Sequence
IKKILSKIKKWLK
Physicochemical Analysis
1626.12 Da
10.70
5.75
5.54
0.4426
-0.31
0.79
-0.16
0.88
150.00
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
604.66
-0.06
22.0
21.0
62.0
115.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0120220 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterobacter cloacae CGMCC 1.58
100 μM
MIC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0122568 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B. cereus
12.5 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0125975 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E.cloacae
>100 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0136135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (50% Hemolysis at >500 microM, Human erythrocytes (<1% Hemolysis at 3.125 microM, Human embryonic kidney HEK293T cells (15% Killing at 3.125 microM
500 μM
Hemolysis
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
RECORD: Rec_0136177 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa CGMCC 1.860
150 μM
MBC
PMID31824473;32023094;23710779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31824473/
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