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MYP_025889
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Basic Information
Atrial natriuretic factor
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C128H207N45O39S2
Standard
Sequence
SLRRSSCFGGRIDRIGAQSGLGCNSFRY
Physicochemical Analysis
3064.42 Da
10.66
3.44
3.20
0.1229
-0.40
0.64
-0.18
82.88
59.29
0.1071
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1403.38
-19.96
55.0
45.0
103.0
214.0
3.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0200228 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 14.3%, E 7.1%, T 60.7%, C 17.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0231592 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Natriuretic peptide
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-23
Bio-Activity Profile
Natriuretic Vasodilator
Radioimmunoassay
Rabbit plasma, in vivo; 192 s
PMID2521208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2521208/
RECORD: Rec_0274537 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-23
Bio-Activity Profile
Natriuretic
Radioimmunoassay and RP-HPLC
Rat blood plasma (infused into fumoral vein and right carotid artery), in vivo; 25.2 s
PMID1697165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1697165/
RECORD: Rec_0293489 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Natriuretic peptide
9986
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Cardiovascular
RECORD: Rec_0402338 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Natriuretic peptide
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-23
Bio-Activity Profile
Natriuretic Vasodilator
Radioimmunoassay
(Dose i/v injected)Mice (WKY) plasma, in vivo; 241.8 s
PMID1664804 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1664804/
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