‹ ›
MYP_025889
← PREVIOUS NEXT → BACK
Basic Information
Atrial natriuretic factor
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C128H207N45O39S2
Standard
Sequence
SLRRSSCFGGRIDRIGAQSGLGCNSFRY
Physicochemical Analysis
3064.42 Da
10.66
3.44
3.20
0.1229
-0.40
0.64
-0.18
82.88
59.29
0.1071
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1403.38
-19.96
55.0
45.0
103.0
214.0
3.0
29.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0085613 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Atrial natriuretic factor
9986
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
noncanonical stereochemical modification [Modified]
7-23
6:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation ACE inhibitory
Experimental: 0.42±0.03 minutes; /25.2 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PMID2934062;1697165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2934062/
RECORD: Rec_0091866 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]; Mus musculus [Animal]; Oryctolagus cuniculus [Animal]
10116, 10090, 9986
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0128320 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Natriuretic peptide
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Cardiovascular
Evidence URLhttps://www.uniprot.org/uniprotkb/ANF_MOUSE/entry
RECORD: Rec_0163629 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Atrial natriuretic factor
9986
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
noncanonical stereochemical modification [Modified]
7-23
6:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation ACE inhibitory
adipose tissue
Experimental: 0.42±0.03 minutes; /25.2 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PMID2934062;1697165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2934062/
RECORD: Rec_0180355 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
natriuretic peptide family
10116; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone natriuretic peptide family Neuropeptide signaling
PaperPDB 1T34 structural record; X-ray; 2.95 A; chain H; residues 7-27
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3