Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length201 amino acids

Chemical FormulaC962H1558N252O284S9

DescriptionStandard

        MQVVICFLMILTHTYADYPALKTVLSEKGLRDVSQMMAVWIQSKLKSTTIPEVHGGVDIGIGTVHYVISNHDGGSLDLAVYNIKIQTLLELGDDTGRVSITTVSCSDGIGGVNIQFHGGARSGTIDVHVLAAAKFSVVKPDGMLVPLFRLDVDGSFSGSALIDKKHLTGAFNMKKVLQSAALQLPYQTVMQLVSTLSVVSL
    

Molecular Weight21486.76 Da

Isoelectric Point (pI)6.64

Net Charge (pH 7.0)-0.90

Net Charge (pH 7.4) -1.54

Charge Density (pH 7.0) -0.0045

GRAVY Index0.38

Hydrophobic Moment 0.70

Boman Index0.21

Instability Index26.48

Aliphatic Index 112.39

Aromaticity 0.0597

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173403 VERIFIED: NO

Provenance & Taxonomy

OrganismLabeo rohita [Bacterium]

FamilyBPI

Tax ID84645

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence