Peptide Database

Peptide NameHepcidin (60-85), PC-hepc

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC116H193N45O29S9

DescriptionStandard

        QGSPARCRFCCRCCPRMRGCGICCRF
    

Molecular Weight2970.64 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.68

Net Charge (pH 7.4) 5.36

Charge Density (pH 7.0) 0.2185

GRAVY Index-0.07

Hydrophobic Moment 0.65

Boman Index-0.28

Instability Index29.00

Aliphatic Index 18.85

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1207.96

LogP -15.99

H-bond Donors 53.0

H-bond Acceptors 44.0

Rotatable Bonds 94.0

Heavy Atoms 199.0

Ring Count 4.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414658 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHepcidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus CGMCC 1.363

Activity6 μM

MethodMIC

RECORD: Rec_0420955 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHepcidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetFusarium graminearum CGMCC 3.349

Activity24 μM

MethodMBC

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