Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length841 amino acids

Chemical FormulaC4110H6546N1054O1196S40

DescriptionStandard

        MFLCWCLSLVALIPLTTSTNPGVKVKLTAKGIEYGRQLAVASILQKLKTIKLDDMSGKVKVSPIGKVKYSLTKKDSGSFNLNANDISFSTSLSIKSDQTGRPVVNSLDCGANVGKMSVHFKGGASWLYNLFSKYIDSAIRKAMQKEICPLVANAVSDLNNNLKTLNVLAKVDKFAEIEYSMVASPAVSKTSIDFGLKGEFYNIGKHQEPPFSPEVFSLPPQVNNMLYIGVSSFTTESAAFVYNTAGALSLYITDDMIPQGSPIRLNTRTFGLFIPQRFPGLMMKLLVKTVKTPVITFEPNNATVQTFASVTAYAIQPNATLAPLFVLNLDSSVSARVFVSGMRLAGAVTLNKMDLTLGTSYVGDFQVSSLDSIFQMVLKMVVIPRMNVQLAKGYPLPTIGKMKLVNTQLLVLKDYVMIGTDVQFTVKMFLCWCLSLVALIPLTTSTNPGVKVKLTAKGIEYGRQLAVASILQKLKTIKLDDVSGKLNADDISFSTSLSIMTDPTGRPAVNSINCGANVGKMSVRFRGGASWLYNLFKKSISSALRKAMQKKICPLVANAVSDLNNNLKTLNVLAKVDKFAEIEYSMVASPAVSKTSIDFGLKGEFYNIGKHQEPPFSPAAFSLPPQVNNMLYIGVSSFPIESAAFVYNTAGALSLDITDDMMGKAPVIMFEPNNATVQTFASVTAYAIQPNATLAPLFVLNLVGYTAGVINKKPFVWFYVGNCLTILSLQDSSVSARVFVSGMRMDLTLGTSDVGDFQVGTLSTIFQTVLNFVVIPRVNGIPSSDTWKDEAGEHSAAGPEGPRDDWDRCSVHGLSGISGSFQFCTMKTQSQFNSLTMRNNE
    

Molecular Weight91142.88 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)19.85

Net Charge (pH 7.4) 19.04

Charge Density (pH 7.0) 0.0236

GRAVY Index0.17

Hydrophobic Moment 0.76

Boman Index0.15

Instability Index29.15

Aliphatic Index 95.26

Aromaticity 0.0880

Extinction Coeff. Reduced 71280.00

Extinction Coeff. Oxidized 71905.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416880 VERIFIED: NO

Provenance & Taxonomy

OrganismDissostichus mawsoni [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria