Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC377H598N108O100S7

DescriptionStandard

        MRIAVLLFTIFFFMSHVLQARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCFLPLGHQPRIESTTPKKD
    

Molecular Weight8467.90 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)3.73

Net Charge (pH 7.4) 3.27

Charge Density (pH 7.0) 0.0511

GRAVY Index-0.13

Hydrophobic Moment 0.43

Boman Index-0.03

Instability Index49.81

Aliphatic Index 78.77

Aromaticity 0.0959

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3333.29

LogP -28.92

H-bond Donors 121.0

H-bond Acceptors 114.0

Rotatable Bonds 279.0

Heavy Atoms 592.0

Ring Count 15.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395923 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Bacterium]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence