Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC774H1200N216O210S14

DescriptionStandard

        MRSLLLVLVVLVLLSCVPAVRGGVNNEIRQMYYSCWRTRGVCKTSCASNELFHILCDDIDVCCIKPEHMPPLVEPEHQRHWTLVWSPSFGDSIGMGVIGSGDSGCSGNSGLGLARVNAIRLEGFWIFTQFQRLGHTICRYFQVLQNYMGFGWIR
    

Molecular Weight17340.04 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.86

Net Charge (pH 7.4) 1.24

Charge Density (pH 7.0) 0.0121

GRAVY Index0.20

Hydrophobic Moment 0.83

Boman Index0.14

Instability Index47.15

Aliphatic Index 94.81

Aromaticity 0.1039

Extinction Coeff. Reduced 33460.00

Extinction Coeff. Oxidized 33960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6770.38

LogP -59.38

H-bond Donors 247.0

H-bond Acceptors 231.0

Rotatable Bonds 560.0

Heavy Atoms 1214.0

Ring Count 32.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0388533 VERIFIED: NO

Provenance & Taxonomy

OrganismDipodomys ordii [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic