Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length455 amino acids

Chemical FormulaC2244H3614N574O639S17

DescriptionStandard

        MSLWRVLALLMLLPATQTTNAGVKVRITQKGLDYGRQIAIATLLEKLKTIKVPDLSGAEKVSPIGKVQYSLTGIQITALGLPKSAVGLVPGTGISLSIGQAYIRMHGNWKVQYLHIVKDSGSFDLFVNGLAITSGIGLKSDETGRPEVNIASCADSISSASVKFRGGASWLYSLFSSYIDKAIRDTLQNDENFLAKVDKYAVVEYSMVQSPVITQSSIDFSLKGEFYSIGKRKEPPFSAKTFSLPPLASNMLYIGVSEFTANSAGFTYNNAGALSLFITDDMIPPSSPIRLNTRTFGAFIPQIAKRYPRMMMKLLVKMVKAPSITFQQNITTIQASGTITAYAIQPNTTLSPLFILNVGVSFSSLVYVTGVKLSGTVSLNKMDMTLGQSYVGPFQVKSLDKIVLMVLKMVVIPKVNARLQQGFPLPSIGKMNLVNTRVQVLKDFMLIGTDVQFTG
    

Molecular Weight49403.26 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)18.66

Net Charge (pH 7.4) 18.24

Charge Density (pH 7.0) 0.0410

GRAVY Index0.22

Hydrophobic Moment 0.79

Boman Index0.17

Instability Index32.29

Aliphatic Index 102.81

Aromaticity 0.0857

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 38850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285653 VERIFIED: NO

Provenance & Taxonomy

OrganismDenticeps clupeoides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence