Peptide Database

Peptide NameHelokinestatin

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC53H82N14O13

DescriptionStandard

        GPPYQPLVPR
    

Molecular Weight1123.30 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0759

GRAVY Index-0.81

Hydrophobic Moment 0.33

Boman Index-0.00

Instability Index59.24

Aliphatic Index 68.00

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 415.28

LogP -2.40

H-bond Donors 12.0

H-bond Acceptors 14.0

Rotatable Bonds 27.0

Heavy Atoms 80.0

Ring Count 5.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213692 VERIFIED: NO

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]; Heloderma horridum [Animal]; Heloderma suspectum cinctum [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist

TargetB2

RECORD: Rec_0221804 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic