Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC335H525N101O100S2

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMGTGGVVSLPEEASAQTQERLRPYNVIKDDSSHFDRKKRFPNK
    

Molecular Weight7631.50 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.62

Charge Density (pH 7.0) 0.0440

GRAVY Index-0.94

Hydrophobic Moment 0.56

Boman Index-0.19

Instability Index55.95

Aliphatic Index 56.72

Aromaticity 0.0896

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3275.58

LogP -35.32

H-bond Donors 115.0

H-bond Acceptors 107.0

Rotatable Bonds 254.0

Heavy Atoms 538.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132413 VERIFIED: YES

Provenance & Taxonomy

OrganismPagrus major [Animal]

FamilyProgonadoliberin

Tax ID143350

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour