Peptide Database

Peptide NameEsculentin-2EV1

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC371H619N97O113S6

DescriptionStandard

        MFTMKKSLLLLFFLGTISLSLCQEERAADEEDNGEVEEAKRGLFTILKGAAKLIGKAVAKEAGKSGLELMACKVTNQC
    

Molecular Weight8438.86 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0065

GRAVY Index0.09

Hydrophobic Moment 0.64

Boman Index0.07

Instability Index21.52

Aliphatic Index 97.69

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3406.50

LogP -30.80

H-bond Donors 120.0

H-bond Acceptors 119.0

Rotatable Bonds 301.0

Heavy Atoms 587.0

Ring Count 4.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222689 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana exiliversabilis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence