Peptide Database

Peptide NameCycloviolacin O16

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H194N30O40S7

DescriptionStandard

        GLPTCGETCTLGTCYVPDCSCSWPICMK
    

Molecular Weight2969.50 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0463

GRAVY Index0.35

Hydrophobic Moment 0.20

Boman Index0.22

Instability Index49.91

Aliphatic Index 52.14

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1080.67

LogP -12.32

H-bond Donors 43.0

H-bond Acceptors 46.0

Rotatable Bonds 87.0

Heavy Atoms 201.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0303614 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)