‹ ›
MYP_025590
← PREVIOUS NEXT → BACK
Basic Information
LF-19
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
19 amino acids
C91H143N25O39S
Standard
Sequence
LEGQEEEEDNRDSSMKLSF
Physicochemical Analysis
2243.32 Da
4.05
-5.22
-5.44
-0.2750
-1.60
0.22
-0.38
97.03
41.05
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1083.01
-13.37
36.0
35.0
81.0
156.0
1.0
20.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0082415 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Chromogranin/secretogranin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secretory granule peptide Neuropeptide precursor
Evidence URLhttps://www.uniprot.org/uniprotkb/CMGA_HUMAN/entry
RECORD: Rec_0265750 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
LF
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
14:Phosphoserine; 15:Methionine sulfoxide
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
Mammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for LF-19 (Homo sapiens): PMID 18541522,12442257 PMID18541522;12442257 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18541522/
RECORD: Rec_0269406 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0287939 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
LF
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
14:Phosphoserine; 15:Methionine sulfoxide
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
cells and noradrenergic neurons
Mammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for LF-19 (Homo sapiens): PMID 15326220,12442257 PMID15326220;12442257 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15326220/
RECORD: Rec_0340769 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 15.8%, E 0.0%, T 47.4%, C 36.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/