MYP_025586
HYL
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
▸
Antibacterial
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Anti-Gram-positive
Antimicrobial
▸
Antifungal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
Venom / Toxin
▸
General toxin
▸
Cytotoxicity
Standard
16 amino acids
C75H135N21O19S2
Standard
GIMSSLMKKLAAHIAK
1699.13 Da
10.30
2.84
2.59
0.1778
0.56
0.54
0.20
60.42
116.25
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
647.02
-4.61
23.0
25.0
61.0
117.0
1.0
15.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0422748
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HYL
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
Stapled: Ⓧ(11) and Ⓧ (15) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Cytotoxicity
HPDE6c7 Human Pancreatic Duct Epithelial Cell
3.45±0.20 μg/mL
IC50
RECORD: Rec_0423154
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Hylaeus signatus [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antifungal
Candida albicans
18 μM
MIC
Showing 2 records on this page · Page 7 of 7