Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 15.6

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC172H289N55O55S6

DescriptionStandard

        QIDTNVKCSGSSKCVKICIDRYNTRGAKCINGRCTCYP
    

Molecular Weight4199.86 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.40

Charge Density (pH 7.0) 0.1236

GRAVY Index-0.44

Hydrophobic Moment 0.67

Boman Index-0.19

Instability Index-1.64

Aliphatic Index 58.95

Aromaticity 0.0526

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1829.81

LogP -25.01

H-bond Donors 71.0

H-bond Acceptors 66.0

Rotatable Bonds 141.0

Heavy Atoms 288.0

Ring Count 3.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133433 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Disulfide8-29; 14-34; 18-36

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Pathogenesis-associated Host defense