Peptide Database

Peptide Nameanalog 4 (Derived from Ib-AMP2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC91H134N34O17

DescriptionStandard

        WGRRGWGKGRRYVRW
    

Molecular Weight1976.26 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.3839

GRAVY Index-1.85

Hydrophobic Moment 0.80

Boman Index-0.56

Instability Index96.29

Aliphatic Index 19.33

Aromaticity 0.2667

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 873.84

LogP -6.07

H-bond Donors 36.0

H-bond Acceptors 23.0

Rotatable Bonds 62.0

Heavy Atoms 142.0

Ring Count 7.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409135 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsThe 'k' in sequence is Lys peptoid residue (Nlys) (NH2-CH2-CH2-CH2-CH2-NH-CH2-COOH)

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli(KCTC 1682)

Activity8 μM

MethodMIC

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