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MYP_025539
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Basic Information
analog 4 (Derived from Ib-AMP2)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C91H134N34O17
Standard
Sequence
WGRRGWGKGRRYVRW
Physicochemical Analysis
1976.26 Da
12.00
5.76
5.55
0.3839
-1.85
0.80
-0.56
96.29
19.33
0.2667
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
873.84
-6.07
36.0
23.0
62.0
142.0
7.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009500 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is Lys peptoid residue (Nlys) (NH2-CH2-CH2-CH2-CH2-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium(KCTC 1926)
4 μM
MIC
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0023175 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is Lys peptoid residue (Nlys) (NH2-CH2-CH2-CH2-CH2-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0095372 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is Lys peptoid residue (Nlys) (NH2-CH2-CH2-CH2-CH2-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0157055 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is Lys peptoid residue (Nlys) (NH2-CH2-CH2-CH2-CH2-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
RECORD: Rec_0185622 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is Lys peptoid residue (Nlys) (NH2-CH2-CH2-CH2-CH2-NH-CH2-COOH)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA)(CCARM 3543)
2 μM
MIC
PMID19778562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19778562/
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