Peptide Database

Peptide NameSLAY-screened peptide P712

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC101H158N30O29S2

DescriptionStandard

        AACCRSQNVSLNLLFTFNRY
    

Molecular Weight2320.65 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.78

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.0888

GRAVY Index0.16

Hydrophobic Moment 0.40

Boman Index0.00

Instability Index65.47

Aliphatic Index 83.00

Aromaticity 0.1500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 993.30

LogP -11.48

H-bond Donors 37.0

H-bond Acceptors 33.0

Rotatable Bonds 74.0

Heavy Atoms 162.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419541 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/