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MYP_025437
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Basic Information
XMP.629 (XOMA-629)
Antimicrobial ▸ Antibacterial
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KLFRXQAKX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0432893 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae ATCC 10031
8 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Tables 4-5 PatentUS 2008/0107717 A1
RECORD: Rec_0432894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae ATCC 35088
2 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Tables 4-5 PatentUS 2008/0107717 A1
RECORD: Rec_0432895 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus sobrinus ATCC 27607
2 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Tables 4-5 PatentUS 2008/0107717 A1
RECORD: Rec_0432896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Propionibacterium acnes ATCC 6919
2 μg/mL
MBC (NCCLS broth-dilution/bactericidal assay)
PaperUS20080107717A1, Example 2, Table 7 PatentUS 2008/0107717 A1
RECORD: Rec_0432897 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Propionibacterium acnes clindamycin-resistant C767
1 μg/mL
MIC (NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Table 7 PatentUS 2008/0107717 A1
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