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MYP_025437
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Basic Information
XMP.629 (XOMA-629)
Antimicrobial ▸ Antibacterial
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KLFRXQAKX
Physicochemical Analysis
0.00 Da
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0223830 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
9606
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Propionibacterium acnes ATCC 6919
1 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperCationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin.Eur J Clin Microbiol Infect Dis (2012) PMID21964560 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21964560/ PatentUS 2008/0107717 A1
RECORD: Rec_0418779 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
9606
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPotential of immunomodulatory host defense peptides as novel anti-infectives.Trends in Biotechnology(2009) PMID19683819 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19683819/ PatentUS 2008/0107717 A1
RECORD: Rec_0432865 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Actinobacillus actinomycetemcomitans ATCC 43718
4 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Tables 4-5 PatentUS 2008/0107717 A1
RECORD: Rec_0432866 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Bacteroides fragilis ATCC 25285
16 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Tables 4-5 PatentUS 2008/0107717 A1
RECORD: Rec_0432867 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
BPI-derived
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
D-3-(1-naphthyl)-alanine at positions 5 and 9
Bio-Activity Profile
Antimicrobial Antibacterial
Burkholderia cepacia ATCC 25416
32 μg/mL
MIC (standardized NCCLS broth-dilution assay)
PaperUS20080107717A1, Example 2, Tables 4-5 PatentUS 2008/0107717 A1
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