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MYP_025389
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Basic Information
Hecate AM V
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
23 amino acids
C119H226N32O24
Standard
Sequence
VALALKALKKLAKKLKKLAKKAL
Physicochemical Analysis
2489.27 Da
10.90
8.72
8.50
0.3793
0.28
0.82
-0.06
-12.58
157.39
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.70
-2.68
33.0
33.0
96.0
175.0
0.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042673 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK / Hecate / Shiva peptide family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
SW-480
MTT-MTS assay
PaperCancerPPD exact sequence record; Hecate AM V PatentUS_06875744_B2
RECORD: Rec_0064991 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7
84 μg/mL
LD50
PaperShort bioactive peptides Evidence URLhttps://patents.google.com/patent/US6875744B2/en PatentUS6875744B2
RECORD: Rec_0077650 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0250988 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Anticancer
RECORD: Rec_0281854 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK / Hecate / Shiva peptide family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HeLa
190.0 μg/mL
LD50 / MTT-MTS assay
PaperCancerPPD exact sequence record; KAL V / Hecate variants PatentUS_06875744_B2
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