Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC463H761N129O123S7

DescriptionStandard

        MRLLLIIAILLFQKFTVTEQLKRCWNQYIQGYCRKICRTTEVREVLCENGRYCCINLAELEERKKITKPPRPKLRTLALTFSQDYL
    

Molecular Weight10327.24 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)7.45

Net Charge (pH 7.4) 7.12

Charge Density (pH 7.0) 0.0866

GRAVY Index-0.20

Hydrophobic Moment 0.74

Boman Index-0.10

Instability Index30.31

Aliphatic Index 104.30

Aromaticity 0.0930

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4151.36

LogP -30.67

H-bond Donors 153.0

H-bond Acceptors 138.0

Rotatable Bonds 352.0

Heavy Atoms 722.0

Ring Count 12.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0230423 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence