Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length382 amino acids

Chemical FormulaC1871H2943N493O534S9

DescriptionStandard

        MSAAHQPQLQKGLWGFSLLLLASFTQPVKGEDGGLKVQVTQKGLEYAKDFGLEMLKVFAKKEQIQDISGSYNVPLLGAVSYTMSGIRVTQFEVTHSTAAFLEGTGLNLTIHNAQVSLSSRWSLSSWLASEDGTVDISLNRLFLSSLLGLGKDARGRPRVSYAGCHSALGDVELKFHGGKSWLYNLLAAALKGILQTEVNKEGEFFQVRGRPGPLLPAPFHLPNQPDSMVLLGISEFFANSAAFAYFMSGALRVNYTGRMIPKTVPFRLNTKNLGVFIPELNKEFPDMEMEIHIAAQKPPVLSIHPGSLEGAAFASVEAFAVLPNANLASAFLLNIEANLTGQVFLRPVQGGTSIGNIAGSLALKSFHLSVEKSSIGEIKVTV
    

Molecular Weight41175.95 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)2.32

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0061

GRAVY Index0.12

Hydrophobic Moment 0.59

Boman Index0.17

Instability Index35.47

Aliphatic Index 98.32

Aromaticity 0.0890

Extinction Coeff. Reduced 32430.00

Extinction Coeff. Oxidized 32430.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349470 VERIFIED: NO

Provenance & Taxonomy

OrganismPogona vitticeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria