MYP_025269
Neurotoxin BcIV
Venom / Toxin
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General toxin
▸
Toxin
Standard
41 amino acids
C207H298N56O57S6
Standard
GLPCDCHGHTGTYWLNYYSKCPKGYGYTGRCRYLVGSCCYK
4675.31 Da
8.83
3.87
3.46
0.0943
-0.57
0.46
-0.01
16.56
35.61
0.1951
15930.00
16305.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1807.90
-17.72
72.0
69.0
141.0
326.0
13.0
41.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0007564
VERIFIED: NO
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-38; 6-31; 21-29
Bio-Activity Profile
Toxin
RECORD: Rec_0432832
VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-38; 6-31; 21-29
Bio-Activity Profile
Toxin
Neurotoxin
Paralytic
Callinectes danae (swimming crab)
≈2000 μg/kg
Minimal lethal dose / crab paralysis bioassay
RECORD: Rec_0432833
VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-38; 6-31; 21-29
Bio-Activity Profile
Toxin
Neurotoxin
Ion-channel modulation
Callinectes danae crab leg nerves
Crab leg nerve action-potential electrophysiology
RECORD: Rec_0432834
VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-38; 6-31; 21-29
Bio-Activity Profile
Toxin
Neurotoxin
Inactive on mammalian Na+ currents
GH3 mammalian cells; voltage-gated Na+ currents
Na+ current electrophysiology (inactive)