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MYP_025260
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Basic Information
K12 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Standard
12 amino acids
C66H127N25O13
Standard
Sequence
VRLRIRVAVIRK
Physicochemical Analysis
1478.87 Da
12.00
4.73
4.52
0.3944
0.44
0.17
-0.33
25.22
178.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
657.04
-3.96
26.0
18.0
52.0
104.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317132 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
RECORD: Rec_0329992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
6 μg/mL
MIC
PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
RECORD: Rec_0333446 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic antibiofilm peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Pseudomonas aeruginosa
2.706 μM
Crystal violet assay
PaperBroad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response PMID24852171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24852171/
RECORD: Rec_0345157 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella
6 μg/mL
MIC
PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
RECORD: Rec_0357452 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella
6 μg/mL
MIC
PaperPubMed PMID: 17052614 PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
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