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MYP_025260
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Basic Information
K12 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Standard
12 amino acids
C66H127N25O13
Standard
Sequence
VRLRIRVAVIRK
Physicochemical Analysis
1478.87 Da
12.00
4.73
4.52
0.3944
0.44
0.17
-0.33
25.22
178.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
657.04
-3.96
26.0
18.0
52.0
104.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068906 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 9017656 B2 Evidence URLhttps://patents.google.com/patent/US9017656B2/en PatentUS 9017656 B2
RECORD: Rec_0107280 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
6 μg/mL
MIC
PaperPubMed PMID: 17052614 PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
RECORD: Rec_0159697 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus epidermidis
1.6 μg/mL
MIC
PaperPubMed PMID: 17052614 PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
RECORD: Rec_0252564 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperBaAMPs: the database of biofilm-active antimicrobial peptides PMID25760404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25760404/
RECORD: Rec_0263827 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
3 μg/mL
MIC
PMID17052614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17052614/
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