Peptide Database

Peptide NameSLAY-screened peptide P3022

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC106H154N26O30S2

DescriptionStandard

        DHHCTIFISLADWNCLYTLA
    

Molecular Weight2336.64 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.08

Net Charge (pH 7.4) -2.42

Charge Density (pH 7.0) -0.1042

GRAVY Index0.53

Hydrophobic Moment 0.25

Boman Index0.32

Instability Index31.67

Aliphatic Index 107.50

Aromaticity 0.1500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 887.98

LogP -5.84

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 70.0

Heavy Atoms 164.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213708 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/