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MYP_025214
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Basic Information
Dermaseptin-DA4 (DRS-DA4; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C133H228N40O38S2
Standard
Sequence
GMWSKIKNAGKAAKAAAKAAGKAALGAVSEAM
Physicochemical Analysis
3059.61 Da
10.30
4.76
4.54
0.1487
0.11
0.58
0.13
2.44
70.94
0.0312
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1258.18
-14.33
44.0
45.0
107.0
213.0
2.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279631 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
rat blood cells
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01697
RECORD: Rec_0284004 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ML35p
5 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01697
RECORD: Rec_0319078 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli 363 ATCC 11775
5 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01697
RECORD: Rec_0326973 VERIFIED: NO
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Chemotactic
RECORD: Rec_0365708 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 59.4%, E 0.0%, T 18.8%, C 21.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-negative Chemotactic
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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