Peptide Database

Peptide NameNL2

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC41H73N13O15S2

DescriptionStandard

        ASCDKCQLKG
    

Molecular Weight1052.23 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0775

GRAVY Index-0.54

Hydrophobic Moment 0.16

Boman Index-0.22

Instability Index27.85

Aliphatic Index 49.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 477.88

LogP -6.69

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 37.0

Heavy Atoms 71.0

Ring Count 0.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307076 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targetinhibition of strand transfer catalyzed by integrase

Activity2000 μM

MethodIC50

RECORD: Rec_0398724 VERIFIED: YES