Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2313H3675N641O723S12

DescriptionStandard

        MQQQRVNADLETAKITEPQRVENARLTAEAAEKAARDRRISEEIAATEAKRQRMENERLAEQERQRVEGTKQQVSEASCAQQASAWQNRFTLPALQPSGSAQYSFAASGMSAVGEAAELHNSFLAAQEQLSAIATISASGSVAAMIALGIYQTKVGESSERPPGWNVSPKFVGSISLSAMGLPATESLASQGEMALPVRMRIIDAKDWIGCTEIYAVKTGVAGVLPKVKVGAAQYDESTGVYTFTTDSTPPRTLIFTPAQPPGAETRPILAPPGSTPATLQHTGEMIIKPVITPTILPLPQLYARDFHDYIIWFPADSGLEPVYVYLNSPYGKTTAKGKYSGRDFNPDKAGGPIKNLDWKEIKIRGEGVDEVKLHTRRFGELEDNKLMIERLEKILTNKLTATDIDKHFYTHEIRELERYRMLGIPDDVNDKSVWNDAHTATLEDFKINEKTQPLYTSEAEDAYIKAELKNSLGSK
    

Molecular Weight52415.57 Da

Isoelectric Point (pI)5.62

Net Charge (pH 7.0)-7.81

Net Charge (pH 7.4) -8.56

Charge Density (pH 7.0) -0.0164

GRAVY Index-0.46

Hydrophobic Moment 0.68

Boman Index-0.03

Instability Index38.80

Aliphatic Index 78.61

Aromaticity 0.0693

Extinction Coeff. Reduced 55350.00

Extinction Coeff. Oxidized 55475.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329442 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia pestis [Bacterium]

FamilyPyocin/Colicin

Tax ID632

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli