Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC358H557N103O107S3

DescriptionStandard

        QHWSYGLSPGGKRELDGLSETLGNQIVGSFPHVATPCRVLGCAEESPFPKIYRMKGFLDAVTDRENGNRTYKK
    

Molecular Weight8112.07 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)1.92

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.0264

GRAVY Index-0.65

Hydrophobic Moment 0.57

Boman Index-0.08

Instability Index27.38

Aliphatic Index 62.74

Aromaticity 0.0959

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3383.93

LogP -36.24

H-bond Donors 119.0

H-bond Acceptors 114.0

Rotatable Bonds 265.0

Heavy Atoms 571.0

Ring Count 15.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136687 VERIFIED: YES

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyProgonadoliberin

Tax ID13489

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour