MYP_025163
Antifungal cyclic dipeptide
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antifungal
Antiparasitic
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Antimalarial
Antiparasitic
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Antiprotozoal
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Antimalarial
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Anti-Plasmodium
Antiparasitic
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General antiparasitic
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Antiparasitic
Enzyme modulation
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Enzyme inhibition
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Protease inhibition
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
FX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0368258
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X=Hyp
Bio-Activity Profile
Antimicrobial
Anticancer
Not available
RECORD: Rec_0371411
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Morpholine urea
Vinyl sulfone
Homophenylalanine (HPhe)
Bio-Activity Profile
Antimicrobial
Cysteine protease inhibitor
Antiparasitic
Antimalarial
Plasmodium vinckei
1 μM
IC50; Fluorimetry (fluorescence by hydrolysis of benzyloxycarbonyl-Phe-Arg-7-amino-4-methyl-coumarin measured)
RECORD: Rec_0379695
VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
P2: hydroxyproline
Bio-Activity Profile
-
RECORD: Rec_0399493
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
OMe
None
X=Sar
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
RECORD: Rec_0403690
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Morpholine urea
Vinyl sulfone
Lys(eZ)=benzyloxycarbonyl group bound to the lysine epsilon amino group
Bio-Activity Profile
Antimicrobial
Cysteine protease inhibitor
Antiparasitic
Antimalarial
Plasmodium vinckei
0.07 μM
IC50; Fluorimetry (fluorescence by hydrolysis of benzyloxycarbonyl-Phe-Arg-7-amino-4-methyl-coumarin measured)
Showing 5 records on this page · Page 8 of 8