Peptide Database

Peptide NameDefensin-B6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC390H614N116O108S9

DescriptionStandard

        MKTLFFLSVFIFLLLHLSPGKMEILLGSNGGARCDINKKSFDCYHRNGRCRFNCRKREYNNGDCSQYQSCCLPTRNL
    

Molecular Weight8944.34 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)6.61

Net Charge (pH 7.4) 6.17

Charge Density (pH 7.0) 0.0858

GRAVY Index-0.34

Hydrophobic Moment 0.65

Boman Index-0.10

Instability Index50.67

Aliphatic Index 70.91

Aromaticity 0.1169

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3674.94

LogP -38.42

H-bond Donors 136.0

H-bond Acceptors 126.0

Rotatable Bonds 301.0

Heavy Atoms 623.0

Ring Count 13.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224994 VERIFIED: NO

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence