Peptide Database

Peptide NameOctreotide acetate

Function Ontology

Used for treatment of acromegaly

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC40H63N9O15S

DescriptionStandard

        LCYSTEIN
    

Molecular Weight942.04 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.1560

GRAVY Index0.12

Hydrophobic Moment 0.14

Boman Index0.15

Instability Index56.90

Aliphatic Index 97.50

Aromaticity 0.1250

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 408.10

LogP -4.12

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 29.0

Heavy Atoms 65.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094364 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySomatostatin

Tax ID32630

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Disulfide2-7

Other Mods2-hydroxy-1-(hydroxymethyl)

Bio-Activity Profile

Function

Used for treatment of acromegaly

MethodEIA

Half-LifeMice blood serum (oral delivery in 0.5% Intravail), in vivo; 3126 s