Peptide Database

Peptide NameNeutrophil antibiotic peptide NP-5 (Microbicidal peptide NP-5)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC429H710N130O136S8

DescriptionStandard

        MRTLALLAAILLVTLQAQAELHSGMADDGVDQQQPRAQDLDVAVYIKQDETSPLEVLGAKAGVFCTCRGFLCGSGERASGSCTINGVRHTLCCRR
    

Molecular Weight10121.54 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-1.37

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0144

GRAVY Index0.08

Hydrophobic Moment 0.38

Boman Index0.04

Instability Index40.65

Aliphatic Index 94.53

Aromaticity 0.0316

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4284.32

LogP -49.99

H-bond Donors 155.0

H-bond Acceptors 145.0

Rotatable Bonds 340.0

Heavy Atoms 703.0

Ring Count 7.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294055 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9986

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic