Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC384H634N96O107S9

DescriptionStandard

        MKLLLLVFTVTLLLAQVTPVMKCWGKSGRCRTMCKESEVYYLLCNTKAKCCVDPKYVPVEPPKLPNTNTSLESISAV
    

Molecular Weight8596.31 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.12

Charge Density (pH 7.0) 0.0577

GRAVY Index0.22

Hydrophobic Moment 0.62

Boman Index0.10

Instability Index20.05

Aliphatic Index 98.57

Aromaticity 0.0649

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3232.24

LogP -26.28

H-bond Donors 117.0

H-bond Acceptors 121.0

Rotatable Bonds 280.0

Heavy Atoms 596.0

Ring Count 12.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283632 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence