Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1158H1757N259O349S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYSDLPYVAAPFTVPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPTVSLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25147.38 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.14

Net Charge (pH 7.4) -17.48

Charge Density (pH 7.0) -0.0752

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index48.74

Aliphatic Index 99.69

Aromaticity 0.1316

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084015 VERIFIED: NO

Provenance & Taxonomy

OrganismEgretta garzetta [Animal]

FamilyBPI/LBP

Tax ID188379

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria