Peptide Database

Peptide NameL-amino acid oxidase (Bpic-LAAO) (LAO) (EC 1.4.3.2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length498 amino acids

Chemical FormulaC2516H3899N679O763S15

DescriptionStandard

        SLLFLAAVGSCADDRNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIKKFDLRLNEFSQENENAWYFLQNIKKRVREVNKDPGVLEYPVKPSEVGKSAGQLYEESLRKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIEIQQDVKEVTVTYQTSQKETLSVTADYVIVCTTSRAARRITFEPPLPPKKAHALLSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDNYAMGGITTFTPYHFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAATDVNRASENK
    

Molecular Weight56347.94 Da

Isoelectric Point (pI)5.75

Net Charge (pH 7.0)-9.48

Net Charge (pH 7.4) -10.57

Charge Density (pH 7.0) -0.0190

GRAVY Index-0.43

Hydrophobic Moment 0.88

Boman Index-0.02

Instability Index42.43

Aliphatic Index 80.88

Aromaticity 0.1044

Extinction Coeff. Reduced 67730.00

Extinction Coeff. Oxidized 68105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069683 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops pictus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Toxin Hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0142363 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops pictus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Toxin Hemolytic

TargetV. cholerae (Gram-negative)

RECORD: Rec_0330083 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops pictus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Toxin Hemolytic

TargetEnterococcus faecalis (Gram-positive)

RECORD: Rec_0396099 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops pictus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Toxin Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0422406 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops pictus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Toxin Hemolytic

TargetEscherichia coli (Gram-negative)