Peptide Database

Peptide NameSLAY-screened peptide P2906

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC103H166N40O28

DescriptionStandard

        RSRGVINKTYSRNAHVHFRN
    

Molecular Weight2412.67 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.93

Net Charge (pH 7.4) 4.63

Charge Density (pH 7.0) 0.2466

GRAVY Index-1.26

Hydrophobic Moment 0.49

Boman Index-0.45

Instability Index61.23

Aliphatic Index 53.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1157.39

LogP -15.08

H-bond Donors 43.0

H-bond Acceptors 35.0

Rotatable Bonds 80.0

Heavy Atoms 171.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0182630 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/