Peptide Database

Peptide NameSLAY-screened peptide P5598

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC112H167N27O26S

DescriptionStandard

        PCEHAKLLYKIVRQYFPSF
    

Molecular Weight2339.75 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.90

Charge Density (pH 7.0) 0.1071

GRAVY Index-0.15

Hydrophobic Moment 0.75

Boman Index0.05

Instability Index14.57

Aliphatic Index 82.11

Aromaticity 0.2105

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 848.04

LogP -3.21

H-bond Donors 31.0

H-bond Acceptors 30.0

Rotatable Bonds 73.0

Heavy Atoms 166.0

Ring Count 7.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344715 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/