Peptide Database

Peptide NameMtDef4_V5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC220H353N85O63S8

DescriptionStandard

        RTCESQSHKFKGPCARRHNCASVCQTERFSGGRCRGFRRRCFCTTHC
    

Molecular Weight5453.21 Da

Isoelectric Point (pI)9.88

Net Charge (pH 7.0)8.95

Net Charge (pH 7.4) 8.47

Charge Density (pH 7.0) 0.1903

GRAVY Index-0.97

Hydrophobic Moment 0.47

Boman Index-0.43

Instability Index81.10

Aliphatic Index 10.43

Aromaticity 0.0851

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2454.02

LogP -36.01

H-bond Donors 100.0

H-bond Acceptors 83.0

Rotatable Bonds 181.0

Heavy Atoms 376.0

Ring Count 8.0

Amide Bonds 49.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0039609 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetB. cinerea. Recombinant production:yeast:Pichia pastoris: activity tested using recombinant peptide. Antimicrobial robustness: KCl-insensitive:B. cinerea (100 mM), CaCl2-insensitive:B. cinerea (2 mM)