Peptide Database

Peptide NameMagainin-2 [I2G,F5A,A9F,G13I]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC114H180N30O29S

DescriptionStandard

        GGGKALHSFKKFIKAFVGEIMNS
    

Molecular Weight2466.90 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1237

GRAVY Index0.08

Hydrophobic Moment 0.75

Boman Index0.17

Instability Index7.78

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 957.13

LogP -7.89

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 86.0

Heavy Atoms 174.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247542 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus subtilis ATCC 6633

Activity10 μM

MethodMIC

RECORD: Rec_0305185 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus megaterium NRRL B-4272

Activity12 μM

MethodMIC

RECORD: Rec_0328520 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 9144

Activity40 μM

MethodMIC

RECORD: Rec_0331803 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 10536

Activity5 μM

MethodMIC

RECORD: Rec_0375344 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman erythrocytes

Activity50 μM

MethodHemolysis