Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length457 amino acids

Chemical FormulaC2319H3631N619O640S15

DescriptionStandard

        TNPGFMVRITQAGLDYAHQHGIAFLEKELARLKLQDISGDFRIRHVGKVHYELSELDLRSFHLPYSRISLVPNVGLQVSISNAFAEVDGHWRVKFYFIRDHGSFDMKVENVYIKINLRLGSDAEGKPTIETSDCSTRISKVRVHFSGKFGWLYNLFYDAIEPTFRRILESKVCETVARSVRRELQPYARTLPVTARIDAKVGIDYSLVAPPTATAQSLDTGLKGEFFSLAQRSAVPFPPLALALPPDHNRMVYFGASSYFFNTAAFAYHAAGVLVFELTDAMVVSPQNGGLCCCPYTLPAPLQLEKMYPDMPMKLRLSAPSAPFLNIGPEGLSLRPVVDIQAYAILPSSSLAPLFLLSLVSNVSAVVNVKSGHIVGSLQVGRMKLSLKHSDVGTFQVRMLQSIMNIYASSILLPRLNERLAEGFPLPLPDRIQLSNILVRFYQNFLLLGADVHYQPQ
    

Molecular Weight50903.37 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 6.50

Charge Density (pH 7.0) 0.0165

GRAVY Index0.08

Hydrophobic Moment 0.84

Boman Index0.11

Instability Index49.65

Aliphatic Index 100.48

Aromaticity 0.1007

Extinction Coeff. Reduced 37820.00

Extinction Coeff. Oxidized 38070.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416807 VERIFIED: NO

Provenance & Taxonomy

OrganismBucorvus abyssinicus (Northern ground-hornbill) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria