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MYP_024843
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Basic Information
Dybowskin-1CDYa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C73H117N15O16
Standard
Sequence
IIPLPLGYFAKKT
Physicochemical Analysis
1460.80 Da
9.70
1.76
1.55
0.1352
0.60
0.35
0.36
15.30
127.69
0.1538
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
487.44
-0.11
16.0
18.0
44.0
104.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0122350 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Temporin
79015
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E.aerogenes CGMCC 1.876
>100 μM
MIC
PaperIdentification and characterisation of a novel antimicrobial polypeptide from the skin secretion of a Chinese frog (Rana chensinensis).
RECORD: Rec_0126774 VERIFIED: NO
Provenance & Taxonomy
Chinese brown [Animal]
Temporin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0137897 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Temporin
79015
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus AS 1.72
>100 μM
MIC
PaperIdentification and characterisation of a novel antimicrobial polypeptide from the skin secretion of a Chinese frog (Rana chensinensis).
RECORD: Rec_0161862 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Dybowskin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
300.0 μM
HC50
PaperLi-Li Jin et al. / Comparative Biochemistry and Physiology, Part B 154 (2009) 174-178. Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii PMID19539775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19539775/
RECORD: Rec_0201164 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Temporin
79015
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecium CGMCC 1.2334
>100 μM
MIC
PaperIdentification and characterisation of a novel antimicrobial polypeptide from the skin secretion of a Chinese frog (Rana chensinensis).
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