Peptide Database

Peptide NamePhoratoxins A

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC202H332N68O65S6

DescriptionStandard

        KSCCPTTTARNIYNTCRFGGGSRPVCAKLSGCKIISGTKCDSNGHNH
    

Molecular Weight4945.60 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.87

Net Charge (pH 7.4) 5.47

Charge Density (pH 7.0) 0.1249

GRAVY Index-0.52

Hydrophobic Moment 0.64

Boman Index-0.12

Instability Index53.15

Aliphatic Index 43.62

Aromaticity 0.0426

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2163.67

LogP -33.77

H-bond Donors 83.0

H-bond Acceptors 79.0

Rotatable Bonds 162.0

Heavy Atoms 341.0

Ring Count 6.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372510 VERIFIED: YES

Provenance & Taxonomy

OrganismPhoradendron tomentosum [Plant]

FamilyThionin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetMice