Peptide Database

Peptide NameL2 (Ala33 substitution mutant of LALF (32-51))

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC129H196N38O23

DescriptionStandard

        HARIKPTFRRLKWKYKGKFW
    

Molecular Weight2647.18 Da

Isoelectric Point (pI)11.76

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.58

Charge Density (pH 7.0) 0.3921

GRAVY Index-1.31

Hydrophobic Moment 0.59

Boman Index-0.38

Instability Index23.56

Aliphatic Index 44.00

Aromaticity 0.2500

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1023.95

LogP -3.48

H-bond Donors 39.0

H-bond Acceptors 32.0

Rotatable Bonds 87.0

Heavy Atoms 190.0

Ring Count 9.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410892 VERIFIED: YES

Provenance & Taxonomy

OrganismLimulus polyphemus [Animal]; Synthetic [Synthetic]

FamilyLALF-derived

Tax ID6850.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anticancer

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